HSA Human Sheddome Atlas
UniProt · Membrane protein

ADAM8 (Disintegrin and Metalloproteinase Domain-Containing Protein 8)

P78325 · 824 aa ·Signal peptide ·1× TM · 4 predicted cleavages ·13 experimental cleavages

Cleavage peaks

Structure

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AlphaFold · pLDDT

Experimental cleavages

13 unique positions · 13 annotations · 12/13 (92%) covered by peaks
Sources (filter in the plot above): uniprotschaeffer22merops
P1 pos Sources Proteases References
16 uniprot Signal peptidase —
44 schaeffer22 — 36313159
136 schaeffer22 — 36313159
137 schaeffer22 — 36313159
138 schaeffer22 — 36313159
157 schaeffer22 — 36313159
159 schaeffer22 — 36313159
160 schaeffer22 — 36313159
161 schaeffer22 — 36313159
167 schaeffer22 — 36313159
200 merops FURIN 18505722
404 schaeffer22 — 36313159
573 schaeffer22 — 36313159

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Sequence

824 aa
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