HSA Human Sheddome Atlas
UniProt · Membrane protein

DSG2 (Desmoglein-2)

Q14126 · 1118 aa ·Signal peptide ·Propeptide ·1× TM · 10 predicted cleavages ·61 experimental cleavages

Cleavage peaks

Structure

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AlphaFold · pLDDT

Experimental cleavages

35 unique positions · 61 annotations · 29/35 (83%) covered by peaks
Sources (filter in the plot above): ascentschaeffer22uniprotweeks21papermerops
P1 pos Sources Proteases References
23 ascentschaeffer22uniprotweeks21 Signal peptidase 33536314 36313163 33526672
49 ascentpaperschaeffer22uniprotweeks21 33536314 33796845 36313163 33526672
50 schaeffer22 36313163
51 ascentweeks21 33536314 33526672
135 schaeffer22 36313163
163 schaeffer22 36313163
166 schaeffer22 36313163
170 schaeffer22 36313163
172 schaeffer22 36313163
199 schaeffer22weeks21 36313163 33526672
201 ascentschaeffer22weeks21 33536314 36313163 33526672
235 schaeffer22 36313163
242 schaeffer22 36313163
245 schaeffer22 36313163
261 paper 33796845
263 ascentschaeffer22weeks21 33536314 36313163 33526672
278 schaeffer22 36313163
279 paperschaeffer22 33796845 36313163
304 merops GZMB 20526345
321 schaeffer22 36313163
338 ascentweeks21 33536314 33526672
365 ascentweeks21 33536314 33526672
367 schaeffer22 36313163
380 schaeffer22 36313163
403 schaeffer22 36313163
406 schaeffer22 36313163
410 ascentschaeffer22weeks21 33536314 36313163 33526672
413 schaeffer22 36313163
414 weeks21 33526672
448 schaeffer22weeks21 36313163 33526672
468 schaeffer22 36313163
470 ascentweeks21 33536314 33526672
570 ascentpaperschaeffer22weeks21 33536314 33796845 36313163 33526672
588 ascentweeks21 33536314 33526672
589 ascentweeks21 33536314 33526672

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Sequence

1118 aa
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