HSA Human Sheddome Atlas
UniProt · Membrane protein

DSG1 (Desmoglein-1)

Q02413 · 1049 aa ·Signal peptide ·Propeptide ·1× TM · 7 predicted cleavages ·19 experimental cleavages

Cleavage peaks

Structure

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AlphaFold · pLDDT

Experimental cleavages

9 unique positions · 19 annotations · 4/9 (44%) covered by peaks
Sources (filter in the plot above): uniprotmerops
P1 pos Sources Proteases References
23 uniprot Signal peptidase —
49 meropsuniprot KLK4 , FURIN 15389820 12586364
146 merops KLK5 —
197 merops KLK1 —
242 merops KLK5 —
368 merops KLK6 —
422 merops KLK5 , KLK6 —
445 merops KLK1 —
528 merops KLK14 —

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Full JSON

Sequence

1049 aa
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