HSA Human Sheddome Atlas
UniProt · Membrane protein

BACE2 (Beta-Secretase 2)

Q9Y5Z0 · 518 aa ·Signal peptide ·Propeptide ·1× TM · 1 predicted cleavages ·4 experimental cleavages

Cleavage peaks

Structure

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AlphaFold · pLDDT

Experimental cleavages

3 unique positions · 4 annotations · 3/3 (100%) covered by peaks
Sources (filter in the plot above): uniprotschaeffer22hprd+merops+pmap
P1 pos Sources Proteases References
20 uniprot Signal peptidase
22 schaeffer22 36313163
62 hprd+merops+pmapuniprot BACE2 11316808 10591213 11083922 11423558 16305800 16816112

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Sequence

518 aa
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