HSA Human Sheddome Atlas
UniProt · Membrane protein

DAG1 (Dystroglycan 1)

Q14118 · 895 aa ·Signal peptide ·1× TM · 6 predicted cleavages ·15 experimental cleavages

Cleavage peaks

Structure

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AlphaFold · pLDDT

Experimental cleavages

11 unique positions · 15 annotations · 6/11 (55%) covered by peaks
Sources (filter in the plot above): ascent+weeks21uniprotschaeffer22papermeropsmerops+uniprot
P1 pos Sources Proteases References
29 ascent+weeks21uniprot Signal peptidase 33536314
489 schaeffer22 36313159
557 paper 33796845
575 schaeffer22 36313159
586 schaeffer22 36313159
653 meropsuniprot DAG1 , Alpha-dystroglycan , autolysis 12798792 17905726
692 schaeffer22 36313159
703 schaeffer22 36313159
715 ascent+weeks21merops+uniprot MMP9 33536314 19946898
716 ascent+weeks21 33536314
717 ascent+weeks21 33536314

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Sequence

895 aa
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