HSA Human Sheddome Atlas
UniProt · Membrane protein

LRP1 (Prolow-Density Lipoprotein Receptor-Related Protein 1)

Q07954 · 4544 aa ·Signal peptide ·1× TM · 28 predicted cleavages ·15 experimental cleavages

Cleavage peaks

Structure

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AlphaFold · pLDDT

Experimental cleavages

6 unique positions · 15 annotations · 1/6 (17%) covered by peaks
Sources (filter in the plot above): uniprotascentweeks21meropspaperhprd
P1 pos Sources Proteases References
19 uniprot Signal peptidase
1834 ascentweeks21 33536314 33526672
1911 merops S01.280
1950 merops S01.280
2509 paper 33796845
3943 hprdmeropsuniprot FURIN , PCSK2 , PCSK4 , PCSK6 , PCSK5 , PCSK7 , Low-density lipoprotein receptor-related protein 1 515 kDa subunit 2112085 8546712 18505722

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Sequence

4544 aa
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