HSA Human Sheddome Atlas
UniProt · Membrane protein

NOTCH2 (Neurogenic Locus Notch Homolog Protein 2)

Q04721 · 2471 aa ·Signal peptide ·1× TM · 5 predicted cleavages ·11 experimental cleavages

Cleavage peaks

Structure

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AlphaFold · pLDDT

Experimental cleavages

8 unique positions · 11 annotations · 8/8 (100%) covered by peaks
Sources (filter in the plot above): uniprotschaeffer22ascent+weeks21paperweeks21hprd
P1 pos Sources Proteases References
25 uniprot Signal peptidase
360 schaeffer22 36313159
1608 ascent+weeks21paperschaeffer22 33536314 33796845 36313159
1622 schaeffer22 36313159
1651 schaeffer22 36313159
1662 schaeffer22weeks21 36313159 33536314
1665 hprd 11518718
1666 uniprot Notch 2 extracellular truncation

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Sequence

2471 aa
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