UniProt · Membrane protein

GSDMD (Gasdermin-D)

P57764 · 484 aa ·4× TM · 5 predicted cleavages ·6 experimental cleavages

Cleavage peaks

Domain source Stringency Domain labels Peak lines Peak labels

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Colour: Topology pLDDT

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AlphaFold · pLDDT

4 unique positions · 6 annotations · 2/4 (50%) covered by peaks

Sources (filter in the plot above): uniprotmerops

P1 pos	Sources	Proteases	References
`87`	uniprot	CASP3 or CASP7 , Gasdermin-D, p13	28045099 28392147 37327784
`193`	uniprot	enterovirus 71 (EV71) Protease 3C and coronavirus SARS-CoV-2 proteinase nsp5	28679757 35594856
`275`	meropsuniprot	CASP1 , caspases CASP1, CASP4, CASP5 and CASP8	20173201 26375003 32109412 38599239 29898893
`290`	uniprot	papain	35794369

484 aa

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