HSA Human Sheddome Atlas
UniProt · Membrane protein

MMP14 (Matrix Metalloproteinase-14)

P50281 · 582 aa ·Signal peptide ·Propeptide ·1× TM · 1 predicted cleavages ·19 experimental cleavages

Cleavage peaks

Structure

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AlphaFold · pLDDT

Experimental cleavages

14 unique positions · 19 annotations · 2/14 (14%) covered by peaks
Sources (filter in the plot above): uniprotmeropsmerops+uniprot
P1 pos Sources Proteases References
20 uniprot Signal peptidase —
49 merops MMP2 17938169
60 merops MMP2 17938169
78 merops M35.004 —
103 merops M35.004 —
108 merops PLG 9037191
111 meropsmerops+uniprot MMP14 , M10.039 , PLG , PCSK2|PCSK4|PCSK5|PCSK6|PCSK7 , FURIN 12514192 24698179 9037191 18505722 8804434
118 merops MMP14 12514192
129 merops MMP14 12514192
221 merops MMP14 12514192
255 merops MMP14 12004057
283 merops MMP14 12514192
284 merops MMP14 —
298 merops MMP14 12514192

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Sequence

582 aa
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