UniProt · Membrane protein

PMEL (Melanocyte Protein PMEL)

P40967 · 661 aa ·Signal peptide ·1× TM · 3 predicted cleavages ·22 experimental cleavages

Cleavage peaks

Domain source Stringency Domain labels Peak lines Peak labels

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Colour: Topology pLDDT

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AlphaFold · pLDDT

18 unique positions · 22 annotations · 4/18 (22%) covered by peaks

Sources (filter in the plot above): merops+uniprotmeropsuniprot

P1 pos	Sources	Proteases	References
`24`	merops+uniprot	XS26.001	8179825
`42`	merops	XT01.001	15001714
`43`	merops	XT01.001	15001714
`46`	merops	XT01.001	15001714
`205`	merops	XT01.001	16393993
`206`	merops	XT01.001	16393993
`207`	merops	ERAP2 , XT01.001	12799365 16393993
`209`	merops	ERAP2 , XT01.001	12799365 16393993
`210`	merops	ERAP2 , XT01.001	12799365 16393993
`211`	merops	ERAP2 , XT01.001	12799365 16393993
`213`	merops	XT01.001	16393993
`217`	merops	XT01.001	16393993
`219`	merops	XT01.001	16393993
`220`	merops	XT01.001	16393993
`467`	uniprot	M-alpha	—
`469`	uniprot	furin-like proprotein convertase	12732614
`470`	uniprot	M-beta	—
`583`	uniprot	ADAM metalloproteinases	19047044

661 aa

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