HSA Human Sheddome Atlas
UniProt · Membrane protein

EPCAM (Epithelial Cell Adhesion Molecule)

P16422 · 314 aa ·Signal peptide ·1× TM · 4 predicted cleavages ·13 experimental cleavages

Cleavage peaks

Structure

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AlphaFold · pLDDT

Experimental cleavages

10 unique positions · 13 annotations · 9/10 (90%) covered by peaks
Sources (filter in the plot above): schaeffer22paperuniprotmerops
P1 pos Sources Proteases References
18 schaeffer22 — 36313159
21 paperschaeffer22 — 33796845 36313159
22 schaeffer22 — 36313159
23 schaeffer22uniprot Signal peptidase 36313159
51 schaeffer22 — 36313159
80 schaeffer22 — 36313159
81 meropsschaeffer22 KLK4 15389820 36313159
163 schaeffer22 — 36313159
214 paper — 33796845
250 schaeffer22 — 36313159

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Sequence

314 aa
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