HSA Human Sheddome Atlas
UniProt · Membrane protein

ACE (Angiotensin-Converting Enzyme)

P12821 · 1306 aa ·Signal peptide ·1× TM · 11 predicted cleavages ·7 experimental cleavages

Cleavage peaks

Structure

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AlphaFold · pLDDT

Experimental cleavages

3 unique positions · 7 annotations · 2/3 (67%) covered by peaks
Sources (filter in the plot above): uniprothprdhprd+uniprotmeropspaper
P1 pos Sources Proteases References
29 uniprot Signal peptidase 2558109
1166 hprduniprot Cleavage 8253769 7499427
1232 hprd+uniprotmeropspaper Cleavage , ADAM17 10769174 26554003

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Full JSON

Sequence

1306 aa
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