HSA Human Sheddome Atlas
UniProt · Membrane protein

CD74 (HLA Class II Histocompatibility Antigen Gamma Chain)

P04233 · 296 aa ·1× TM · 3 predicted cleavages ·23 experimental cleavages

Cleavage peaks

Structure

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AlphaFold · pLDDT

Experimental cleavages

21 unique positions · 23 annotations · 8/21 (38%) covered by peaks
Sources (filter in the plot above): schaeffer22meropsuniprot
P1 pos Sources Proteases References
68 schaeffer22 — 36313159
69 schaeffer22 — 36313159
82 merops CTSS 17081125
84 merops CTSS 17081125
92 merops LGMN 12705852
94 merops CTSS 17081125
96 merops CTSS 17081125
97 uniprot Class-II-associated invariant chain peptide 1448172
108 merops CTSS 17081125
110 merops CTSS 17081125
114 merops CTSS 17081125
116 merops CTSS 17081125
120 uniprot Class-II-associated invariant chain peptide 1448172
121 merops CTSS 17081125
129 merops CTSS 17081125
144 schaeffer22 — 36313159
147 schaeffer22 — 36313159
159 meropsschaeffer22 CTSS 17081125 36313159
170 meropsschaeffer22 CTSS 17081125 36313159
171 merops LGMN 12705852
199 merops CTSS 17081125

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Sequence

296 aa
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