HSA Human Sheddome Atlas
UniProt · Membrane protein

CD74 (HLA Class II Histocompatibility Antigen Gamma Chain)

P04233 · 296 aa ·1× TM · 3 predicted cleavages ·26 experimental cleavages

Cleavage peaks

Structure

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AlphaFold · pLDDT

Experimental cleavages

21 unique positions · 26 annotations · 8/21 (38%) covered by peaks
Sources (filter in the plot above): topfindschaeffer22meropsuniprot
P1 pos Sources Proteases References
68 topfindschaeffer22 23264352 36313163
69 schaeffer22 36313163
82 merops CTSS 17081125
84 merops CTSS 17081125
92 merops LGMN 12705852
94 merops CTSS 17081125
96 merops CTSS 17081125
97 uniprot Class-II-associated invariant chain peptide 1448172
108 merops CTSS 17081125
110 merops CTSS 17081125
114 merops CTSS 17081125
116 merops CTSS 17081125
120 uniprot Class-II-associated invariant chain peptide 1448172
121 merops CTSS 17081125
129 merops CTSS 17081125
144 schaeffer22 36313163
147 schaeffer22 36313163
159 meropsschaeffer22 CTSS 17081125 36313163
170 meropsschaeffer22 CTSS 17081125 36313163
171 merops LGMN 12705852
199 merops CTSS 17081125

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Sequence

296 aa
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