HSA Human Sheddome Atlas
UniProt · Membrane protein

TGFA (Protransforming Growth Factor Alpha)

P01135 · 160 aa ·Signal peptide ·Propeptide · 0 predicted cleavages ·26 experimental cleavages

Cleavage peaks

Structure

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AlphaFold · pLDDT

Experimental cleavages

13 unique positions · 26 annotations · 2/13 (15%) covered by peaks
Sources (filter in the plot above): uniprothprdmerops+pmapschaeffer22meropshprd+merops+pmap
P1 pos Sources Proteases References
23 uniprot Signal peptidase
39 hprdmerops+pmapschaeffer22uniprot ADAM10 , Removed in mature form 11823465 12590602 36313163
50 merops IDE 19896952
53 merops IDE 19896952
54 merops IDE 19896952
56 merops IDE 19896952
59 merops IDE 19896952
60 merops IDE 19896952
73 merops IDE 19896952
74 merops IDE 19896952
79 merops IDE 19896952
89 hprd+merops+pmapuniprot ADAM17 , Transforming growth factor alpha 11823465
160 uniprot Removed in mature form

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Sequence

160 aa
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