UniProt · Membrane protein

EREG (Proepiregulin)

O14944 · 169 aa ·Signal peptide ·Propeptide · 3 predicted cleavages ·8 experimental cleavages

Cleavage peaks

Domain source Stringency Domain labels Peak lines Peak labels

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Colour: Topology pLDDT

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AlphaFold · pLDDT

4 unique positions · 8 annotations · 3/4 (75%) covered by peaks

Sources (filter in the plot above): uniprotmerops

P1 pos	Sources	Proteases	References
`29`	uniprot	Signal peptidase	—
`62`	meropsuniprot	ADAM17	11823465
`108`	meropsuniprot	ADAM17 , Epiregulin	11823465
`169`	uniprot	Removed in mature form	—

169 aa

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