{"uniprot":"Q3B7S5","gene":"SMIM21","title":"SMIM21 (Small Integral Membrane Protein 21)","length":101,"sequence":["MDQYVSTAPPRFPIAQLGTFKQDSAGMGRIFKGNLLQKKALTTFENEHHIRFFTLLVLFHVMVLLRNHSRIQGVSEDWKRANSIFRNFLRLKSSRNTAEAE"],"topology":[{"pos":1,"topology":"outside"},{"pos":2,"topology":"outside"},{"pos":3,"topology":"outside"},{"pos":4,"topology":"outside"},{"pos":5,"topology":"outside"},{"pos":6,"topology":"outside"},{"pos":7,"topology":"outside"},{"pos":8,"topology":"outside"},{"pos":9,"topology":"outside"},{"pos":10,"topology":"outside"},{"pos":11,"topology":"outside"},{"pos":12,"topology":"outside"},{"pos":13,"topology":"outside"},{"pos":14,"topology":"outside"},{"pos":15,"topology":"outside"},{"pos":16,"topology":"outside"},{"pos":17,"topology":"outside"},{"pos":18,"topology":"outside"},{"pos":19,"topology":"outside"},{"pos":20,"topology":"outside"},{"pos":21,"topology":"outside"},{"pos":22,"topology":"outside"},{"pos":23,"topology":"outside"},{"pos":24,"topology":"outside"},{"pos":25,"topology":"outside"},{"pos":26,"topology":"outside"},{"pos":27,"topology":"outside"},{"pos":28,"topology":"outside"},{"pos":29,"topology":"outside"},{"pos":30,"topology":"outside"},{"pos":31,"topology":"outside"},{"pos":32,"topology":"outside"},{"pos":33,"topology":"outside"},{"pos":34,"topology":"outside"},{"pos":35,"topology":"outside"},{"pos":36,"topology":"outside"},{"pos":37,"topology":"outside"},{"pos":38,"topology":"outside"},{"pos":39,"topology":"outside"},{"pos":40,"topology":"outside"},{"pos":41,"topology":"outside"},{"pos":42,"topology":"outside"},{"pos":43,"topology":"outside"},{"pos":44,"topology":"outside"},{"pos":45,"topology":"outside"},{"pos":46,"topology":"outside"},{"pos":47,"topology":"outside"},{"pos":48,"topology":"outside"},{"pos":49,"topology":"membr"},{"pos":50,"topology":"membr"},{"pos":51,"topology":"membr"},{"pos":52,"topology":"membr"},{"pos":53,"topology":"membr"},{"pos":54,"topology":"membr"},{"pos":55,"topology":"membr"},{"pos":56,"topology":"membr"},{"pos":57,"topology":"membr"},{"pos":58,"topology":"membr"},{"pos":59,"topology":"membr"},{"pos":60,"topology":"membr"},{"pos":61,"topology":"membr"},{"pos":62,"topology":"membr"},{"pos":63,"topology":"membr"},{"pos":64,"topology":"membr"},{"pos":65,"topology":"membr"},{"pos":66,"topology":"outside"},{"pos":67,"topology":"inside"},{"pos":68,"topology":"inside"},{"pos":69,"topology":"inside"},{"pos":70,"topology":"inside"},{"pos":71,"topology":"inside"},{"pos":72,"topology":"inside"},{"pos":73,"topology":"inside"},{"pos":74,"topology":"inside"},{"pos":75,"topology":"inside"},{"pos":76,"topology":"inside"},{"pos":77,"topology":"inside"},{"pos":78,"topology":"inside"},{"pos":79,"topology":"inside"},{"pos":80,"topology":"inside"},{"pos":81,"topology":"inside"},{"pos":82,"topology":"inside"},{"pos":83,"topology":"inside"},{"pos":84,"topology":"inside"},{"pos":85,"topology":"inside"},{"pos":86,"topology":"inside"},{"pos":87,"topology":"inside"},{"pos":88,"topology":"inside"},{"pos":89,"topology":"inside"},{"pos":90,"topology":"inside"},{"pos":91,"topology":"inside"},{"pos":92,"topology":"inside"},{"pos":93,"topology":"inside"},{"pos":94,"topology":"inside"},{"pos":95,"topology":"inside"},{"pos":96,"topology":"inside"},{"pos":97,"topology":"inside"},{"pos":98,"topology":"inside"},{"pos":99,"topology":"inside"},{"pos":100,"topology":"inside"},{"pos":101,"topology":"inside"}],"curves":{"stringent":[{"pos":1,"prob":2.973496e-12},{"pos":2,"prob":2.750934e-12},{"pos":3,"prob":2.528372e-12},{"pos":4,"prob":2.55712e-12},{"pos":5,"prob":2.528372e-12},{"pos":6,"prob":2.147146e-12},{"pos":7,"prob":1.76592e-12},{"pos":8,"prob":1.923365e-12},{"pos":9,"prob":2.08081e-12},{"pos":10,"prob":2.116989e-12},{"pos":11,"prob":2.153169e-12},{"pos":12,"prob":2.34077e-12},{"pos":13,"prob":2.528372e-12},{"pos":14,"prob":2.55712e-12},{"pos":15,"prob":2.585869e-12},{"pos":16,"prob":2.528372e-12},{"pos":17,"prob":2.585869e-12},{"pos":18,"prob":3.261501e-12},{"pos":19,"prob":3.261501e-12},{"pos":20,"prob":3.261501e-12},{"pos":21,"prob":3.261501e-12},{"pos":22,"prob":3.261501e-12},{"pos":23,"prob":3.619744e-12},{"pos":24,"prob":3.619744e-12},{"pos":25,"prob":3.619744e-12},{"pos":26,"prob":3.261501e-12},{"pos":27,"prob":2.711275e-12},{"pos":28,"prob":2.618487e-12},{"pos":29,"prob":2.263701e-12},{"pos":30,"prob":2.245973e-12},{"pos":31,"prob":2.188641e-12},{"pos":32,"prob":1.962892e-12},{"pos":33,"prob":1.945037e-12},{"pos":34,"prob":1.409814e-12},{"pos":35,"prob":1.136119e-12},{"pos":36,"prob":2.726406e-13},{"pos":37,"prob":2.438361e-13},{"pos":38,"prob":1.155777e-13},{"pos":39,"prob":1.461445e-14},{"pos":40,"prob":1.16907e-14},{"pos":41,"prob":5.509355e-15},{"pos":42,"prob":2.483119e-15},{"pos":43,"prob":2.281561e-15},{"pos":44,"prob":1.328246e-15},{"pos":45,"prob":1.328246e-15},{"pos":46,"prob":1.328246e-15},{"pos":47,"prob":1.328246e-15},{"pos":48,"prob":1.328246e-15},{"pos":49,"prob":1.328246e-15},{"pos":50,"prob":1.328246e-15},{"pos":51,"prob":1.328246e-15},{"pos":52,"prob":2.24804e-15},{"pos":53,"prob":3.196401e-15},{"pos":54,"prob":7.088388e-15},{"pos":55,"prob":1.085499e-14},{"pos":56,"prob":2.415741e-14},{"pos":57,"prob":4.789124e-14},{"pos":58,"prob":1.058717e-13},{"pos":59,"prob":1.149614e-13},{"pos":60,"prob":1.149614e-13},{"pos":61,"prob":1.149614e-13},{"pos":62,"prob":1.240422e-13},{"pos":63,"prob":1.294581e-13},{"pos":64,"prob":1.294581e-13},{"pos":65,"prob":1.294581e-13},{"pos":66,"prob":1.240422e-13},{"pos":67,"prob":1.149614e-13},{"pos":68,"prob":9.762269e-14},{"pos":69,"prob":9.762269e-14},{"pos":70,"prob":9.148547e-14},{"pos":71,"prob":6.469016e-14},{"pos":72,"prob":6.290396e-14},{"pos":73,"prob":4.691517e-14},{"pos":74,"prob":3.875778e-14},{"pos":75,"prob":3.514427e-14},{"pos":76,"prob":2.930058e-14},{"pos":77,"prob":1.587443e-14},{"pos":78,"prob":9.767982e-15},{"pos":79,"prob":9.260955e-15},{"pos":80,"prob":7.705886e-15},{"pos":81,"prob":6.293922e-15},{"pos":82,"prob":5.154301e-15},{"pos":83,"prob":3.234511e-15},{"pos":84,"prob":3.204886e-15},{"pos":85,"prob":3.204886e-15},{"pos":86,"prob":3.204886e-15},{"pos":87,"prob":3.204886e-15},{"pos":88,"prob":2.205862e-15},{"pos":89,"prob":1.206838e-15},{"pos":90,"prob":1.107471e-15},{"pos":91,"prob":1.008105e-15},{"pos":92,"prob":1.107471e-15},{"pos":93,"prob":1.206838e-15},{"pos":94,"prob":2.205862e-15},{"pos":95,"prob":3.204886e-15},{"pos":96,"prob":4.14456e-15},{"pos":97,"prob":5.084234e-15},{"pos":98,"prob":5.560276e-15},{"pos":99,"prob":6.036318e-15},{"pos":100,"prob":7.821573e-15},{"pos":101,"prob":9.606827e-15}],"moderate":[{"pos":1,"prob":2.973496e-12},{"pos":2,"prob":2.750934e-12},{"pos":3,"prob":2.528372e-12},{"pos":4,"prob":2.55712e-12},{"pos":5,"prob":2.528372e-12},{"pos":6,"prob":2.147146e-12},{"pos":7,"prob":1.76592e-12},{"pos":8,"prob":1.923365e-12},{"pos":9,"prob":2.08081e-12},{"pos":10,"prob":2.116989e-12},{"pos":11,"prob":2.153169e-12},{"pos":12,"prob":2.34077e-12},{"pos":13,"prob":2.528372e-12},{"pos":14,"prob":2.55712e-12},{"pos":15,"prob":2.585869e-12},{"pos":16,"prob":2.528372e-12},{"pos":17,"prob":2.585869e-12},{"pos":18,"prob":3.261501e-12},{"pos":19,"prob":3.261501e-12},{"pos":20,"prob":3.261501e-12},{"pos":21,"prob":3.261501e-12},{"pos":22,"prob":3.261501e-12},{"pos":23,"prob":3.619744e-12},{"pos":24,"prob":3.619744e-12},{"pos":25,"prob":3.619744e-12},{"pos":26,"prob":3.261501e-12},{"pos":27,"prob":2.711275e-12},{"pos":28,"prob":2.618487e-12},{"pos":29,"prob":2.263701e-12},{"pos":30,"prob":2.245973e-12},{"pos":31,"prob":2.188641e-12},{"pos":32,"prob":1.962892e-12},{"pos":33,"prob":1.945037e-12},{"pos":34,"prob":1.409814e-12},{"pos":35,"prob":1.136119e-12},{"pos":36,"prob":2.726406e-13},{"pos":37,"prob":2.438361e-13},{"pos":38,"prob":1.155777e-13},{"pos":39,"prob":1.461445e-14},{"pos":40,"prob":1.16907e-14},{"pos":41,"prob":5.509355e-15},{"pos":42,"prob":2.483119e-15},{"pos":43,"prob":2.281561e-15},{"pos":44,"prob":1.328246e-15},{"pos":45,"prob":1.328246e-15},{"pos":46,"prob":1.328246e-15},{"pos":47,"prob":1.328246e-15},{"pos":48,"prob":1.328246e-15},{"pos":49,"prob":1.328246e-15},{"pos":50,"prob":1.328246e-15},{"pos":51,"prob":1.328246e-15},{"pos":52,"prob":2.24804e-15},{"pos":53,"prob":3.196401e-15},{"pos":54,"prob":7.088388e-15},{"pos":55,"prob":1.085499e-14},{"pos":56,"prob":2.415741e-14},{"pos":57,"prob":4.789124e-14},{"pos":58,"prob":1.058717e-13},{"pos":59,"prob":1.149614e-13},{"pos":60,"prob":1.149614e-13},{"pos":61,"prob":1.149614e-13},{"pos":62,"prob":1.240422e-13},{"pos":63,"prob":1.294581e-13},{"pos":64,"prob":1.294581e-13},{"pos":65,"prob":1.294581e-13},{"pos":66,"prob":1.240422e-13},{"pos":67,"prob":1.149614e-13},{"pos":68,"prob":9.762269e-14},{"pos":69,"prob":9.762269e-14},{"pos":70,"prob":9.148547e-14},{"pos":71,"prob":6.469016e-14},{"pos":72,"prob":6.290396e-14},{"pos":73,"prob":4.691517e-14},{"pos":74,"prob":3.875778e-14},{"pos":75,"prob":3.514427e-14},{"pos":76,"prob":2.930058e-14},{"pos":77,"prob":1.587443e-14},{"pos":78,"prob":9.767982e-15},{"pos":79,"prob":9.260955e-15},{"pos":80,"prob":7.705886e-15},{"pos":81,"prob":6.293922e-15},{"pos":82,"prob":5.154301e-15},{"pos":83,"prob":3.234511e-15},{"pos":84,"prob":3.204886e-15},{"pos":85,"prob":3.204886e-15},{"pos":86,"prob":3.204886e-15},{"pos":87,"prob":3.204886e-15},{"pos":88,"prob":2.205862e-15},{"pos":89,"prob":1.206838e-15},{"pos":90,"prob":1.107471e-15},{"pos":91,"prob":1.008105e-15},{"pos":92,"prob":1.107471e-15},{"pos":93,"prob":1.206838e-15},{"pos":94,"prob":2.205862e-15},{"pos":95,"prob":3.204886e-15},{"pos":96,"prob":4.14456e-15},{"pos":97,"prob":5.084234e-15},{"pos":98,"prob":5.560276e-15},{"pos":99,"prob":6.036318e-15},{"pos":100,"prob":7.821573e-15},{"pos":101,"prob":9.606827e-15}],"permissive":[{"pos":1,"prob":2.973496e-12},{"pos":2,"prob":2.750934e-12},{"pos":3,"prob":2.528372e-12},{"pos":4,"prob":2.55712e-12},{"pos":5,"prob":2.528372e-12},{"pos":6,"prob":2.147146e-12},{"pos":7,"prob":1.76592e-12},{"pos":8,"prob":1.923365e-12},{"pos":9,"prob":2.08081e-12},{"pos":10,"prob":2.116989e-12},{"pos":11,"prob":2.153169e-12},{"pos":12,"prob":2.34077e-12},{"pos":13,"prob":2.528372e-12},{"pos":14,"prob":2.55712e-12},{"pos":15,"prob":2.585869e-12},{"pos":16,"prob":2.528372e-12},{"pos":17,"prob":2.585869e-12},{"pos":18,"prob":3.261501e-12},{"pos":19,"prob":3.261501e-12},{"pos":20,"prob":3.261501e-12},{"pos":21,"prob":3.261501e-12},{"pos":22,"prob":3.261501e-12},{"pos":23,"prob":3.619744e-12},{"pos":24,"prob":3.619744e-12},{"pos":25,"prob":3.619744e-12},{"pos":26,"prob":3.261501e-12},{"pos":27,"prob":2.711275e-12},{"pos":28,"prob":2.618487e-12},{"pos":29,"prob":2.263701e-12},{"pos":30,"prob":2.245973e-12},{"pos":31,"prob":2.188641e-12},{"pos":32,"prob":1.962892e-12},{"pos":33,"prob":1.945037e-12},{"pos":34,"prob":1.409814e-12},{"pos":35,"prob":1.136119e-12},{"pos":36,"prob":2.726406e-13},{"pos":37,"prob":2.438361e-13},{"pos":38,"prob":1.155777e-13},{"pos":39,"prob":1.461445e-14},{"pos":40,"prob":1.16907e-14},{"pos":41,"prob":5.509355e-15},{"pos":42,"prob":2.483119e-15},{"pos":43,"prob":2.281561e-15},{"pos":44,"prob":1.328246e-15},{"pos":45,"prob":1.328246e-15},{"pos":46,"prob":1.328246e-15},{"pos":47,"prob":1.328246e-15},{"pos":48,"prob":1.328246e-15},{"pos":49,"prob":1.328246e-15},{"pos":50,"prob":1.328246e-15},{"pos":51,"prob":1.328246e-15},{"pos":52,"prob":2.24804e-15},{"pos":53,"prob":3.196401e-15},{"pos":54,"prob":7.088388e-15},{"pos":55,"prob":1.085499e-14},{"pos":56,"prob":2.415741e-14},{"pos":57,"prob":4.789124e-14},{"pos":58,"prob":1.058717e-13},{"pos":59,"prob":1.149614e-13},{"pos":60,"prob":1.149614e-13},{"pos":61,"prob":1.149614e-13},{"pos":62,"prob":1.240422e-13},{"pos":63,"prob":1.294581e-13},{"pos":64,"prob":1.294581e-13},{"pos":65,"prob":1.294581e-13},{"pos":66,"prob":1.240422e-13},{"pos":67,"prob":1.149614e-13},{"pos":68,"prob":9.762269e-14},{"pos":69,"prob":9.762269e-14},{"pos":70,"prob":9.148547e-14},{"pos":71,"prob":6.469016e-14},{"pos":72,"prob":6.290396e-14},{"pos":73,"prob":4.691517e-14},{"pos":74,"prob":3.875778e-14},{"pos":75,"prob":3.514427e-14},{"pos":76,"prob":2.930058e-14},{"pos":77,"prob":1.587443e-14},{"pos":78,"prob":9.767982e-15},{"pos":79,"prob":9.260955e-15},{"pos":80,"prob":7.705886e-15},{"pos":81,"prob":6.293922e-15},{"pos":82,"prob":5.154301e-15},{"pos":83,"prob":3.234511e-15},{"pos":84,"prob":3.204886e-15},{"pos":85,"prob":3.204886e-15},{"pos":86,"prob":3.204886e-15},{"pos":87,"prob":3.204886e-15},{"pos":88,"prob":2.205862e-15},{"pos":89,"prob":1.206838e-15},{"pos":90,"prob":1.107471e-15},{"pos":91,"prob":1.008105e-15},{"pos":92,"prob":1.107471e-15},{"pos":93,"prob":1.206838e-15},{"pos":94,"prob":2.205862e-15},{"pos":95,"prob":3.204886e-15},{"pos":96,"prob":4.14456e-15},{"pos":97,"prob":5.084234e-15},{"pos":98,"prob":5.560276e-15},{"pos":99,"prob":6.036318e-15},{"pos":100,"prob":7.821573e-15},{"pos":101,"prob":9.606827e-15}]},"peaks":[],"domains":[],"cleavages":null}